Lumizyme.com


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  • Location: Dublin Ireland
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We found Websites Listing below when search with lumizyme.com on Search Engine

Lumizyme | Patients & Families

Lumizyme ® (alglucosidase alfa) is a medication that replaces a missing or deficient enzyme in people with Pompe disease. If you have Pompe disease, ask your healthcare provider if Lumizyme is an appropriate treatment for you. The information provided on this site is not intended to replace discussions with your healthcare provider. Be sure to ...

Lumizyme.com

Lumizyme | About Lumizyme

Lumizyme consists of the human enzyme GAA, encoded by the most predominant of nine observed haplotypes of the GAA gene. Upon intravenous infusion, carbohydrate groups of the Lumizyme molecules bind to mannose-6-phosphate (M6P) receptors on the cell surface. The Lumizyme molecules are taken by receptor-mediated transport into the lysosomes of muscle …

Lumizyme.com

Lumizyme | Treating Patients

Lumizyme is administered by intravenous infusion, and should be reconstituted, diluted, and administered by a health care professional. Lumizyme is a hydrolytic lysosomal glycogen-specific enzyme indicated for patients with Pompe disease (acid α-glucosidase (GAA) deficiency). Because of the potential risks of infusion reactions as well as more serious adverse events, …

Lumizyme.com

Lumizyme | Prescribing Lumizyme

Lumizyme Full Prescribing Information, Genzyme Corporation; Van der Ploeg et al, A randomized study of alglucosidase alfa in late-onset Pompe’s disease. N Engl J Med 2010, 362;15; 1396-1406. Kishnani PS, Howell RR. Pompe disease in infants and children. J Pediatr 2004; 144:S35-S43. Ausems MG, Verbiest J. Hermans MP, et al. Frequency of glycogen …

Lumizyme.com

FAQs About Lumizyme for Pompe Disease - Pompe …

2021-02-02  · Share article via email Copy article link. Lumizyme (alglucosidase alfa) is an enzyme replacement infusion therapy by Sanofi Genzyme for people with Pompe disease. In the European Union, it is available under the brand name Myozyme. Here are answers to some frequently asked questions about this treatment. How does Lumizyme work? Lumizyme …

Pompediseasenews.com

LUMIZYME (alglucosidase alfa) for Injection

LUMIZYME (alglucosidase alfa) is a lysosomal glycogen-specific enzyme indicated for patients 8 years and older with late (non-infantile) onset Pompe disease (GAA deficiency) who do not have evidence of cardiac hypertrophy. The safety and efficacy of LUMIZYME have not been evaluated in controlled clinical trials in infantile-onset patients, or in late (non-infantile) onset patients less …

Accessdata.fda.gov

Alglucosidase alfa (Lumizyme) - IVX Health

Rev. 9/28/2021 ORLANDO: 844 ALGLUCOSIDASE ALFA (LUMIZYME) ORDERS page 1 of 2 Email [email protected] or fax this form, insurance card (both sides), demographics, recent H&P, labs, and supporting clinicals to: BAY AREA: 844-889-0275 CINCINNATI: 844-9 46-0868 CHICAGO: 312 -253 7244 COLUMBUS: 844-627-2675 HARRISBURG: 844-859-4235 …

Ivxhealth.com

LUMIZYME® (ALGLUCOSIDASE ALFA) ORDER FORM

Fax To: (855) 891-2191 Email To: . [email protected] . Have a Question? Call: (855) 478-1528 . LUMIZYME® (ALGLUCOSIDASE ALFA) ORDER FORM . REFERRAL STATUS

Mppinfusion.com

Lumizyme - Alglucosidase Alfa - Rare Disease Advisor

Lumizyme ® (alglucosidase alfa) is a hydrolytic lysosomal glycogen-specific enzyme indicated for the replacement of the acid alpha-glucosidase (GAA) enzyme in Pompe disease. 1,2 GAA is responsible for hydrolyzing lysosomal glycogen into glucose. GAA is absent or deficient in Pompe disease, which results in the buildup of glycogen in the cells, with higher incidence in muscle …

Rarediseaseadvisor.com

Pompe Disease | Glycogen Storage Disease | Lumizyme

About the Disease. Pompe disease i s an inherited disorder caused by the buildup of glycogen, a complex sugar, in the body's cells, which impairs the ability for affected organs, tissues, and muscles to function normally.. Several different clinical types of Pompe disease have been identified. Classic form, infantile-onset. The classic form of Pompe disease begins within a few …

Orsinispecialtypharmacy.com

Next-generation ERT Nexviazyme Approved by FDA for Late ...

2021-08-09  · Lumizyme is approved in Europe, where it is marketed as Myozyme. Recommended Reading. February 2, 2021 by BNS Staff. FAQs About Lumizyme for Pompe Disease. The European Commission is currently considering an application to approve Nexviazyme. Sanofi is also seeking approval of the medication in Japan. The FDA’s approval …

Pompediseasenews.com

Myozyme, INN-alglucosidase alfa - Europa

Myozyme EMA/58201/2014 Page 3/3 Patients who receive Myozyme may develop antibodies (proteins that are produced in response to Myozyme). The effect of these antibodies on the sa fety and effectiveness of Myozyme is not yet clear.

Ema.europa.eu

Lumizyme-Myozyme Given Early and at Higher Dose May Be ...

2020-05-28  · Lumizyme-Myozyme Given Early and at Higher Dose May Be Best for Infantile-onset Pompe. When administered early and above its recommended dose, Myozyme (alglucosidase alfa, known as Lumizyme in the U.S.) may improve the clinical outcomes and prognosis of people with infantile-onset Pompe disease (IOPD), a study reports.

Pompediseasenews.com

米FDA ポンペ病治療薬Lumizymeが全年齢に適応 REMSを解除 | …

2014-08-12  · 米FDA ポンペ病治療薬Lumizymeが全年齢に適応 REMSを解除 | 米食品医薬品局(FDA)は8月1日、米ジェンザイム社(仏・サノフィ子会社)のポンペ病治療 ...

Mixonline.jp

HIGHLIGHTS OF PRESCRIBING INFORMATION ...

LUMIZYME® (alglucosidase alfa) [see Description (11)] is a hydrolytic lysosomal glycogen-specific enzyme indicated for patients with Pompe disease (acid α-glucosidase [GAA] deficiency). 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dose The recommended dosage of alglucosidase alfa is 20 mg/kg body weight administered every 2 weeks

Products.sanofi.us

Lumizyme Infusion for Pompe Disease | IVX Health

2021-09-21  · Lumizyme is a biologic therapy that is indicated to treat: Pompe disease. Lumizyme replaces the missing acid a-glucosidase (GAA) enzyme that patients with Pompe disease do not produce enough naturally. Lumizyme infusions are given every two weeks, with each infusion typically lasting four hours.

Ivxhealth.com

Lumizyme, Myozyme (Alglucosidase alfa) MCP-267

This policy addresses the coverage of Alglucosidase alfa (Lumizyme, Myozyme) treatment of patients with Pompe disease when appropriate criteria are met. Pompe disease is a rare progressively debilitating and often fatal inherited disorder of glycogen metabolism caused by the absence or marked deficiency of the lysosomal enzyme GAA. a,4,5,6 In the infantile-onset …

Molinahealthcare.com

LUMIZYME - Renal and Urology News

LUMIZYME Warnings/Precautions: Risk of anaphylaxis or severe hypersensitivity reactions; discontinue immediately if develop. Have appropriate …

Renalandurologynews.com

Lumizyme | medyheli

2014-07-29  · Lumizyme Generic Name: alglucosidase alfa (injection) (AL gloo KOE si dase AL fa) Brand Names: Lumizyme, Myozyme What is Lumizyme? Lumizyme (alglucosidase alfa) contains an enzyme that naturally occurs in the body in healthy people. Some people lack this enzyme because of a genetic disorder. Lumizyme helps replace this missing enzyme in such …

Medyheli.wordpress.com

Lumizyme - M.E.G.'s Confessional

My Lumizyme infusions are scheduled for every two weeks, so obviously some arrangements would need to be made. I become terribly fatigued and my muscles start to ache if I miss a treatment. It is a huge set back in my crusade against Pompe when my treatment schedule is interrupted. I started working with my Case Manager at Genzyme months in advance to …

Purplelv93.wordpress.com


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