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Network
- inetnum : 208.91.196.0 - 208.91.197.255
- name : CONFLUENCE-NETWORK-INC
- handle : NET-208-91-196-0-1
- status : Direct Allocation
- created : 2011-04-07
- changed : 2017-03-29
Owner
- organization : Confluence Networks Inc
- handle : CN
- address : Array,Road Town,Tortola,VG1110,VG
Technical support
- handle : TECHA29-ARIN
- name : Tech Admin
- phone : +1-415-358-0891
- email : [email protected]
Abuse
- handle : ABUSE3065-ARIN
- name : Abuse Admin
- phone : +1-415-449-4704
- email : [email protected]
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Host Informations
- IP address: 208.91.197.23
- Location: British Virgin Islands
- Latitude: 18.5
- Longitude: -64.5
- Timezone: America/Tortola
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Forodesine.biz | Easy, Fast and FREE
Domain Name: forodesine.biz: Domain Extension: biz: Top-Level Domain (TLD).biz: TLD Type: Restricted Generic Top-Level Domain (gTLD) Registrar: Network Solutions, LLC
Ipaddress.comforodesine.biz - Worth and traffic estimation | forodesine.biz
2021-01-28 · forodesine.biz was launched at February 28, 2000 and is 22 years and 15 days. It reaches roughly 30 users and delivers about 30 pageviews each month. Its estimated monthly revenue is $0.00.We estimate the value of forodesine.biz to be around $10.00.The domain forodesine.biz uses a Business Organizations suffix and its server(s) are located in British …
Statshow.comForodesine (BCX-1777) | PNP Inhibitor | MedChemExpress
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels. - Mechanism of Action & …
Medchemexpress.comforodesine.biz down? Current problems and status. - DownFor
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Downforeveryoneorjustme.comForodesine | 209799-67-7
Forodesine; CAS Number: 209799-67-7; Linear Formula: C11H14N4O4; find AChemBlock-ADV509447831 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
Sigmaaldrich.comForodesine | 209799-67-7 - Sigma-Aldrich
Forodesine; CAS Number: 209799-67-7; Linear Formula: C11H14N4O4; find AChemBlock-ADV509447831 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
Sigmaaldrich.comForodesine - an overview | ScienceDirect Topics
Forodesine (Immucillin H, 7-(3,4-dihydroxy-5-hydroxymethylpyrrolidyn-2-yl)-3,5-dihydropyrrolo-[3,2-d] pyrimidin-4-one) is a purine nucleoside phosphorylase (PNP) inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell ALL and cutaneous T-cell lymphoma. 124,125 Forodesine was synthesized based on a transition-state …
Sciencedirect.comForodesine, an inhibitor of purine nucleoside phosphorylase, …
2006-10-01 · Forodesine is a 10- to 100-fold more potent inhibitor of human lymphocyte proliferation than other known PNP inhibitors such as PD141955 and BCX-34. 8 Previous studies demonstrated that the cytotoxic activity of forodesine in the presence of dGuo was selective to T lymphocytes. 9 High kinase and low nucleotidase levels make these cells more sensitive to …
Ashpublications.orgFORODESINE AMPLIFIES HOST INNATE IMMUNE RESPONSE …
Forodesine, a novel inhibitor of purine nucleoside phosphorylase (PNP), causes nucleotide pool imbalances by accumulating intracellular deoxyguanosine, thereby resulting in selective apoptosis of T-cells. Recent evidence indicates that specific types of nuclear acids including guanosine and its derivatives act as natural ligands for toll-like receptor 7 (TLR7). So far, it is unclear whether ...
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